Drug Discovery and Development
Course Director: James E. Barrett, Ph.D.
All lectures will be held in Room xxxx, New College Building
| DATE |
TIME |
TOPIC |
| August 26, 2008 |
1:00-2:30 |
Course Overview & ObjectivesThe Drug Discovery, Development and Approval Process
|
| August 28, 2008 |
1:00-2:30 |
Historical Perspectives: The Legacy of the Past and the Evolution of Drug Discovery & Modern Medicine
|
| September 2, 2008 |
1:00-2:30 |
Drug Research Strategy: Organizational Aspects of the Pharmaceutical Industry
|
| September 4, 2008 |
1:00-2:30 |
Target Based Drug Discovery: Diversity of Targets, Identification, Selection, and Validation
|
| September 9, 2008 |
1:00-2:30 |
Chemical and Biological Space: Navigating Chemical Space for Biology and Medicine
|
| September 14, 2008 |
1:00-2:30 |
High Throughput Screening Lead Search & Compound Optimization, Medicinal Chemistry & Chemical Technologies |
| September 16, 2008 |
1:00-2:30 |
The Emergence of Biotechnology: Small molecules vs biologicals
|
| September 21, 2008 |
1:00-2:30 |
Case Studies in Drug Discovery and Development I |
| September 23, 2008 |
1:00-2:30 |
EXAM 1.
|
| September 28, 2008 |
1:00-2:30 |
Preclinical Assessment I: In Vitro & In Vivo Model Systems |
| September 30, 2008 |
1:00-2:30 |
Preclinical Assessment II: Drug Metabolism, Toxicology and Pathology |
| October 7, 2008 |
1:00-2:30 |
The FDA: Regulatory Guidelines and Drug Development: History and Current Status |
| October 9, 2008 |
1:00-2:30 |
Translational Medicine: Strategies, Concepts and the Interface Between Preclinical and Clinical Research
|
| October 14, 2008 |
1:00-2:30 |
Clinical Research I: Phase I Studies First in Humans: Safety & Tolerability
|
| October 16, 2008 |
1:00-2:30 |
Clinical Research II: Phase II Studies & Clinical Trial Designs
|
| October 21, 2008 |
1:00-2:30 |
Clinical Research III: Phase III Studies: Safety and Efficacy
|
| October 23, 2008 |
1:00-2:30 |
Case Studies in Drug Discovery and Development II
|
| October 28, 2008 |
1:00-2:30 |
Therapeutic Areas & Unmet Needs II: Oncology
|
| October 30, 2008 |
1:00-2:30 |
Therapeutic Areas & Unmet Needs I: Central Nervous System
|
| November 4, 2008 |
1:00-2:30 |
Therapeutic Areas & Unmet Needs III: Cardiovascular
|
| November 6, 2008 |
1:00-2:30 |
Project Team Formation: Mock Discovery and Development Project |
| November 11, 2008 |
1:00-2:30 |
Project Team Formation: Mock Discovery and Development Project Report
|
| November 13, 2008 |
1:00-2:30 |
Overview of Commercial and Marketing |
| November 18, 2008 |
1:00-2:30 |
Why drugs fail?
|
| November 20, 2008 |
1:00-2:30 |
Current Status and Emerging Trends in the Pharmaceutical and Biotechnology Industry: Translational Medicine
|
| November 25, 2008 |
1:00-2:30 |
Technology Development and Entrepreneurial Initiatives
|
| November 25, 2008 |
1:00-2:30 |
EXAM 2: Final paper submitted.
|
|