Chair
Neurology
New College Building
245 N. 15th St
Philadelphia PA 19102
Phone: 215-762-7090
Fax: 215-762-3161
Email: robert.schwartzman@drexelmed.edu
Education:
1961: B.A., Harvard College, Cambridge, Massachusetts
1965: M.D., University of Pennsylvania, Philadelphia
Training:
1965-1966 Intern in Medicine, Duke Hospital, Durham, NC
1966-1967 Junior Assistant Resident in Medicine, Duke Hospital, Durham, NC
1967-1969 Resident in Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA
1969-1971 Clinical Associate, NIH, Medical Neurology Branch
Publications
1. Dowell AR, Sieker HO, Schwartzman RJ: Atypical periodic respiration in an obese patient. Arch Int Med 120:591 598, 1967.
2. Schwartzman RJ, Bogdonoff MD: Behavioral and anatomical analysis of vibration sensibility. Exp Neurol 20:42 51, 1968.
3. Schwartzman RJ, Bogdonoff MD: Proprioception and vibration sensibility in the absence of the posterior columns. Arch Neurol 20:349 353, 1969.
4. Schwartzman RJ: Thalamic sensory nuclear ablations in trained monkeys. Arch Neurol 23:419 430, 1970.
5. Schwartzman RJ, Semmes J: The sensory cortex and tactile sensitivity. Exp Neurol 33:147 158, 1971.
6. Schwartz G, Schwartzman RJ: Atrial myxoma. Neurology 22:11 12, 1972.
7. Schwartzman RJ: Somatesthetic recovery following primary somatosensory projection cortex ablations. Arch Neurol 27:340 349, 1972.
8. Engel WK, Borenstein A, DeVivo DC, Schwartzman RJ, Warmolts JR: High single dose alternate day prednisone (HS PRED) in the treatment of the dermatomyositis/ polymyositis complex. Trans Am Neurol Assoc 97:272 275, 1972.
9. Dimancescu MD, Schwartzman RJ: Cerebellopontine influence on the motor system. A functional and anatomical study following section of the brachium pontis in trained Macaque monkeys. Trans Am Neurol Assoc 98:1973.
10. Rosenberg E, Kanner S, Schwartzman RJ, Colsky J: Systemic infection following BCG immunotherapy. Arch Int Med 134:769 771, 1974.
11. Schwartzman RJ: Rehabilitation of infantile hemiplegia. Am J Phys Med 53:75 81, 1974.
12. Fischer KC, Schwartzman RJ: Oral corticosteroids in the treatment of ocular myasthenia gravis. Neurology 24, 795 798, 1974.
13. Zwibel HL, Schwartzman RJ: Evaluation of the nitroblue tetrazolium test as applied to polymorphonuclear leukocytes in the CSF. Neurology 24:995 998, 1974.
14. Brenner R, Schwartzman RJ, Richey ET: Prognostic significance of episodic low amplitude or relatively isoelectric EEG patterns. Diseases of the Nervous System 36:582 587, 1975.
15. Fischer KC, Schwartzman, RJ: Oral corticosteroids in the treatment of ocular myasthenia gravis. Ophthalmology Digest, April, 1975.
16. Weinstein R, Schwartzman RJ, Levey GS: Propranolol induced reversal of bulbar
dysfunction and proximal myopathy in a patient with hyperthyroidism. Ann Int Med 82:540 541, 1975.
17. Spector RH, Schwartzman RJ: The syndrome of benign trigeminal and facial neuropathy. Arch Int Med 135:992, 1975.
18. Schwartzman RJ, Marcos J, Gran B: A functional analysis of cortical motor sensory convergency areas in the monkey. Trans Am Neurol Assoc, June, 1975.
19. Traviesa DC, Schwartzman RJ: Familial benign intracranial hypertension. J Neurol Neurosurg Psychiat 39:420 423, 1976.
20. Fischer KC, Schwartzman RJ: Oral corticosteroids in the treatment of ocular myasthenia gravis. Ann NY Acad Sci 274:652 657, 1976.
21. Spector RH, Davidoff RA, Schwartzman RJ: Phenytoin induced ophthalmoplegia. Neurology 26:1031 1034, 1976.
22. Schwartzman RJ, Kogure K and Busto R: The use of 14C deoxyglucose to measure alterations of brain metabolism in embolic stroke. Stroke 8(1):131, 1977.
23. Menkin M, Schwartzman RJ: Cerebral air embolism. Arch Neurol 34:165, 1977.
24. Bolooki H, Schwartzman RJ: Role of steroids in the management of patients with myasthenia gravis undergoing thymectomy. J Thor and Cardio Surg 75:754 757, 1978.
25. Schwartzman RJ: A behavioral analysis of complete unilateral section of the pyramidal tract at the medullary level in Mucaca Mulatta. Ann Neurol 4:234 244, 1978.
26. Schwartzman RJ, Kogure K, Busto R:The sequential uptake of 14C deoxyglucose in brain after embolic stroke. Experientia 34:1175 1176 (1978) Birkhauser Verlag, Basel (Schweiz)
27. Kogure K, Schwartzman RJ, Scheinberg P, Busto R: The dissociation of cerebral blood flow and metabolism in the early stage of developing cerebral infarction. Transactions of the American Neurological Association 42, 1978.
28. Kogure K, Schwartzman RJ: Seizure propagation and ATP depletion in the rat stroke model. Epilepsia 21:63 72, 1980.
29. Kogure K, Busto R, Schwartzman RJ, Scheinberg P:The dissociation of cerebral blood flow, metabolism, and function in the early stage of developing cerebral infarction. Ann Neurol 8:278 190, 1980.
30. Alexander GM, Schwartzman RJ, Bell RD, Yu J, Rental A: Quantitative measurement of local metabolic rate for glucose utilizing tritiated 2 deoxyglucose. Trans Amer Neurol Assoc, 105:448 451, 1980.
31. Bertoni JM, Alexander GM, Schwartzman RJ: Metrizamide competitively inhibits hexokinase. Trans Amer Neurol Assoc 105:212 220, 1980.
32. Hill JB, Schwartzman RJ: Cerebral infarction and disseminated intravascular coagulation with pheochromocytoma. Arch Neurol 38: 395, 1981.
33. Schwartzman RJ, Greenberg J, Reivich M, Klose KJ, Alexander GM: Functional metabolic mapping of a conditioned motor task in primates utilizing 14C 2 deoxyglucose. Exper Neurol 72:153 162, 1981.
34. Bertoni JM, Schwartzman RJ, Van Horn G, Partin J: Asterixis and encephalopathy following metrizamide myelography: Investigations into possible mechanisms and review of the literature. Ann Neurol 9:366 370, 1981.
35. Alexander GM, Schwartzman RJ, Bell RD, Yu J, Renthal A: Quantitative measurement of local metabolic rate for glucose utilizing tritiated 2 deoxyglucose. Brain Research 223:59 67, 1981.
36. Bell Rd, Alexander G, Schwartzman RJ: Analysis of drug induced tremor utilizing
14C 2 deoxyglucose in the awake rat. Trans Amer Neurol Assoc 106:84 86, 1981.
37. Schwartzman RJ, Alexander GM, Eidelberg E, Yu JJ: Changes in local metabolic rate for glucose in the intact and acutely transected spinal cord. Trans Amer Neurol Assoc 106:342 345, 1981.
38. Schwartzman RJ, Hill JB: The neurological complications of disseminated intravascular coagulation. Neurology 32:791 797, 1982.
39. Bell, RD, Alexander GM, Schwartzman RJ, YU J: The local cerebral metabolism of methylphenidate induced stereotype in the awake rat. Neurol 32:377 381, 1982.
40. Bell RD, Alexander GM, Schwartzman RJ: Methylphenidate decreases local glucose metabolism in the motor cortex. Pharmacol Biochem and Behavior 18:1 5, 1983.
41. Schwartzman RJ, Eidelberg E, Alexander GM, YU J: Regional metabolic changes in the spinal cord related to spinal shock and later hyperreflexia in monkeys. Ann Neurol 14:33 37, 1983.
42. Fariello GT, Schwartzman RJ, Beall SS: Hyperreflexia exacerbated by occlusion of posterior thalamic arteries. Arch Neurol 40:244 246, 1983.
43. Fariello RG, Golden GT, Alexander GM, Schwartzman RJ, Reyes PF: Metabolic correlates of GABAmimetic induced EEG abnormalities. In Fariello RG, Engle J, Lloyd KG, and Quesney LF (eds). Neurotransmitters, Seizures and Epilepsy II. New York, Raven Press, 1984.
44. Alexander GM and Schwartzman RJ: Quantitative computer analysis of autoradiographs utilizing a charge coupled device solid state camera. Neuroscience Methods 12:29 36, 1984.
45. Schwartzman RJ and Alexander GM: Spinal cord metabolism of the NMPTP treated monkey. Brain Research 337:263, 1985.
46. Blum LW, Chambers RA, Schwartzman RJ and Streletz LJ: Progressive multifocal leukoencephalopathy in acquired immune deficiency syndrome. Arch Neurol 42:137 139, 1985.
47. Askanas V, Engel, WK, Teepu S, Husainy T, Kwan Hh, Reddy NB, Schwartzman RJ, Hann CJ: New autosomal dominant non carnitine deficient lipid myoneuropathy with marked, sustained improvement on long chain fatty acid free diet. Neurology 35:66 72, 1985.
48. Schwartzman RJ and Alexander GM: Changes in the Local Cerebral Metabolic Rate for Glucose in the MPTP model of Parkinson's disease. Brain Research 358:137 143, 1985.
49. Tabby DS, Schwartzman RJ. Reflex Sympathetic Dystrophy: A Review of 200 cases. Journal of the American College of Neuropsychiatrists. Feb/Mar 1989 P 20-24.
50. Schwartzman RJ and Alexander GM: The 1CMRg of the CNS in the MPTP model of Parkinson's Disease. VIIIth International Symposium on Parkinson's Disease. Academic Press, Inc., New York, pp 689-693, 1986.
51. Schwartzman RJ, Eidelberg E, and Alexander GM: Asymmetrical regional changes in energy metabolism in the central nervous system during walking. Brain Research 398:113-120, 1986.
52. Brainard GC, Schwartzman, RJ and Alexander GM: Quantitative autoradiographic maps of local cerebral glucose metabolism in awake rats: I. Septal region and anterior hypothalamus. 259:559-570, 1987.
53. Schwartzman, RJ and McLellan TL: Reflex Sympathetic Dystrophy. Arch Neurol 44:555-561, 1987.
54. D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL and Synder SH: Neuromelanin: A role in MPTP induced neurotoxicity. Life Sciences, 40:705-712, 1987.
55. D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL and Synder SH: Evidence for neuromelanin involvement in MPTP induced neurotoxicity. Nature 327(6120):324-326, May, 1987.
56. Schwartzman RJ and Alexander GM: Changes in the local cerebral metabolic rate for glucose in the MPTP primate model of Parkinson's Disease. In: MD Yahr and KJ Bergmann (eds.), Advances in Neurology, Raven Press, NY 45:171-173, 1986.
57. Reyes PF, Dwyer BA, Schwartzman RJ, and Sacchetti T: Mental status changes induced by eye drops in dementia of the Alzheimer type. Journal of Neurology, Neurosurgery and Psychiatry 50:113-115, 1987.
58. D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL and Snyder SH: Evidence for neuromelanin involvement in MPTP-induced neurotoxicity. Nature 327:324-326, 1987.
59. Eidelberg E, Miller AL, Schwartzman RJ, and Alexander GM: The use of measurements of regional glucose metabolism as a tool in studies of motor control. Journal of Neuroscience Methods 21:133-144, 1987.
60. Schwartzman RJ, Alexander GM, Ferraro TN, Grothusen JR, and Stahl SM: Cerebral metabolic changes in the MPTP primate model of Parkinson's disease. Experimental Neurology 102:307-313, 1988.
61. Park CH, Madsen MT, McLellan T, Schwartzman RJ: Iofetamine HCI I-123 brain scanning in stroke: A comparison with transmission CT. Radio Graphics 8:2, 1988.
62. Alexander GM, Grothusen JR and Schwartzman RJ: Flow dependent changes in the effective surface area of microdialysis probes. Life Sciences, 43:595-601, 1988.
63. Alexander GM, Grothusen JR, Zepeda H and Schwartzman RJ: Gyroxin, a neurotoxin from the venom of crotalus durissus terrificus, is a thrombin-like enzyme. Toxicon Vol 26 10:953-960, 1988.
64. Arias LM, Schwartzman RJ, Bartowski R, Tom, CM, Grossman KL: Sufentanil Stellate Ganglion Injection in the Treatment of Refractory Reflex Sympathetic Dystrophy. Regional Anesth 14:90-92, 1989.
65. Barolat G, Schwartzman R, Woo R: Epidural spinal cord stimulation in the management of reflex sympathetic dystrophy. Stereotact Funct Neurosurg 53:29-39, 1989.
66. Schwartzman RJ: Disseminated intravascular coagulation. In: Handbook of Clinical Neurology: Vascular Diseases, Part III. HCN Toole III 30:1-9, 1989.
67. Schwartzman RJ, Kerrigan J: The movement disorder of reflex sympathetic dystrophy. Neurology 40:57-61, 1990.
68. Santo JL, Arias LM, Barolat G, Schwartzman RJ, Grossman K: Bilateral cingulumotomy in the treatment of reflex sympathetic dystrophy. Pain 41:55-59, 1990.
69. Schwartzman RJ: Book Reviews - Reflex Sympathetic Dystrophy. (Edited by M Stanton Hicks, W Janig and RA Boas. Kluwer Academic Publishers Grup/Dordrecht, The Netherlands) Journal of Pain Symptoms Management 6(7):453, 1990.
70. Alexander GM, Brainard L, Gordon SW, Hichens M, Grothusen JG, Schwartzman RJ: Dopamine receptor changes in untreated and (+)-PHNO treated MPTP Parkinsonian primates. Brain Research, 547:181-189, 1991.
71. Bej MD, Schwartzman RJ: Abnormalities of cutaneous blood flow regulation in patients with reflex sympathetic dystrophy as measured by laser Doppler fluxmetry. Archives of Neurology 1991; 48:912-915.
72. Duckett S, Osterholm J, Gonzalez C, Schwartzman RJ. Ossified mucin-secreting choroid plexus adenoma: A case report. Neurosurgery 29:130-132,1991.
73. Webster GF, Schwartzman RJ, Jacoby RA, Uitto JJ. Reflex sympathetic dystrophy: occurrence of inflammatory skin lesions in patients with stage II and III disease. Arch of Dermatology, 127:1541-1544, 1991.
74. Murphy LG, Alexander GM, Schwartzman RJ. Improvement to the Hargreaves paws flick method. Letter to the Editor. Pain 46:347, 1991.
75. Schwartzman RJ: Brachial Plexus Traction Injuries. Hand Clinics 7(3):547-556, 1991.
76. Schwartzman RJ: Reflex sympathetic dystrophy and causalgia. Neurologic Clinics 10:953-973, 1992.
77. Duckett S, Schwartzman RJ, Osterholm J, Rourke LB, Friedman D, McLellan TL. Biopsy diagnosis of familial Alexander's Disease. Pediatric Neurosurgery 343:134-138, 1992.
78. Alexander GM, Schwartzman RJ, Grothusen JR, Brainard DL and Gordon SW: Changes in catecholamines and dopamine uptake sites at different stages of MPTP parkinsonism in monkeys. Brain Research, 625:276-282, 1993.
79. Schwartzman RJ: Reflex sympathetic dystrophy. Current Opinion in Neurology and Neurosurgery 6:531-536, 1993.
80. Webster GF, Iozzo RV, Schwartzman RJ, Tahmoush AJ, Knobler RL, and Jacoby RA: Reflex sympathetic dystrophy: Occurrence of chronic edema and nonimmune bullous skin lesions. J Amer Acade Dermatol 28:29-32, 1993.
81. Alexander GM, Schwartzman RJ, Grothusen JR, Gordon SW: Effect of plasma levels of large neutral amino acids and -adrenergip stimulation on the blood to brain transport of L-dopa in naive and MPTP parkinsonian monkeys. Neurology 44:1491-1499, 1994.
82. Alexander GM, Schwartzman RJ, Nukes TA, Grothusen JR, Hooker MD: B2-adrenergic agonist as adjunct therapy to L-dopa in Parkinson's disease. Neurology 44:1511-1513, 1994.
83. Liu JE, Tahmoush AJ, Roos DB, Schwartzman RJ: Shoulder-arm pain from cervical bands and scalene muscle anomalies. Journal of the Neuorlogical Sciences 128:175- 180, 1995.
84. Zoltick PW, Mayreddy RPR, Chun-Fan C, Northrup B, Khalili K, Schwartzman RJ: Isolation and characterization of a type II JC virus from a brain biopsy of a patient with PML. Journal of Neurovirology 1:307-315, 1995.
85. Schweitzer ME, Mandel S, Schwartzman RJ, Knobler RJ, Tahmoush AJ: Reflex sympathetic dystrophy revisited: MR imaging findings before and after infusion of contrast material. Radiology 195:211-214, 1995.
86. Chancellor MB, Shenot PJ, Rivas DA, Mandel S, Schwartzman RJ: Urological symptomology in patients with reflex sympathetic dystrophy. The Journal of Urology, 155:634-637, 1996.
87. Tartaglino LS, Croul S, Flanders AE, Sweeney JD, Schwartzman RJ, Liem M, Amer A: Idiopathic acute transverse myelitis: MR findings and similarities to Guillain-Barre and ischemia. Radiology 201:661-669, 1996.
88. Tahmoush AJ, Schwartzman RJ, Liu JE, Smullens SN, Hyslop T: Reflex sympathetic dystrophy; long term response to sympathectomy. Neurology 46:169, 199
89. Schwartzman RJ, Liu JE, Smullens SN, Hyslop T, Tahmoush T: Long-term outcome following sympathectomy for complex regional pain syndrome Type I (RSD). J Neurol Sci 150:149-152, 1997.
90. Alexander GM, Grothusen JR, Gordon SW, Schwartzman RJ: Intracerebral microdialysis study of glutamate reuptake in awake, behaving rats. Brain Research 766:1-10, 1997.
91. Monti DA, Herring CL, Schwartzman RJ, Marchese M: Personality assessment of patients with complex regional pain syndrome type 1. Clinical Journal of Pain 14(4):295-302, 1998.
92. Schwartzman RJ, Maleki J: Post-injury neuropathic pain syndromes. Medical Clinics of North America 83(3):597-625, 1999.
93. Schwartzman RJ: Explaining reflex sympathetic dystrophy. Arch Neurol 56:521-522, 1999.
94. Urruttia V, Jichici D, Thomas CE, Nunes LW, Schwartzman RJ: Embolic stroke secondary to an aortic arch tumor. The Journal of Vascular Medicine Angiology 784:T1-T4. 2000.
95. Tahmoush AJ, Schwartzman RJ, Hopp JL, Grothusen JR: Quantitative sensory thresholds in reflex sympathetic dystrophy (Complex regional pain syndrome type 1). Clin J Pain 16:340-344, 2000.
96. Maleki J, LeBel A, Bennett GJ, Schwartzman RJ: Patterns of spread in complex regional pain syndrome, type I (reflex sympathetic dystrophy). Pain 88(3):259-266, 2000.
97. Schwartzman RJ: Neurologic symptoms in complex regional pain. Journal Watch Neurology 2(10):73, 2000.
98. Thomas CE, Jichici D, Petrucci R, Urrutia VC, Schwartzman RJ. Neurologic complications of the Novacor left ventricular assist device. Ann Thorac Surg 72:1311-1315, 2001.
99. Schwartzman RJ, Grothusen J, Kiefer TR, Rohr P: Neuropathic central pain: Epidemiology, etiology and treatment options. Arch Neurol 58:1547-1550, 2001.
100. van de Beek WJ, Schwartzman RJ, van Nes SI, Delhaas EM, van Hilten BJ: Diagnostic criteria utilized in studies of reflex sympathetic dystrophy. Neurology 58:522-526, 2002.
101. Schwartzman RJ, Popescu A. Reflex sympathetic dystrophy. Current Rheumatology Reports 4:165-169, 2002.
102. Hansrote S, Croul S, Selak M, Kalman B, Schwartzman RJ. External ophthalmoplegia
with severe multiorgan involvement associated with the mtDNAA3243G . Journal of Neuroscience 197:63067, 2002.
103. Brannagan TH, Pradhan A, Heiman-Patterson T, Winkelman AC, Styler MJ, Topolsky DL, Crilley PA, Schwartzman RJ, Brodsky I, Gladstone DE. High-dose cyclophosphamide without stem cell rescue for refractory chronic inflammatory demyelinating polyneuropathy (CIDP). Neurology 58(12):1856-1858, 2002.
104. Tahmoush AJ, Amir MS, Connor WW, Farry JK, Didato S, Ulhoa-Cintra A, Vasas JM, Schwartzman RJ, Israel HL, Patrick H. CSF-ACE activity in probable CNS neurosarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 19:191-197, 2002.
105. Schwartzman RJ: The Case for Fibromyalgia – All in a Name? Neurology Reviews 10:10-12, 2002.
106. Tahmoush AJ, Amir MS, Connor WW, Farry JK, Didato S, Ulhoa-Cintra A, Vasas
JM, Schwartzman RJ, Israel HL, Patrick H. CSF-ACE activity in probable CNS neurosarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2002 Oct;19(3):191-7.
107. Koenigsberg RA, Pereira L, Nair B, McCormick D, Schwartzman R: Unusual vertebral artery origins: examples and related pathology. Cather Cardiovasc Interv 59:244-250, 2003.
108. Dey DD, Schwartzman RJ. Reflex sympathetic dystrophy. Physician’s Information and Education Resource Module, American College of Physicians, American Society of Internal Medicine 2003.
109. Schwartzman RJ, Chevlen E, Bengtson K. Thalidomide has activity in treating complex regional pain syndrome. Arch Intern Med 2003; 163:1487-1488.
110. Gladstone DE, Brannagan TH, Schwartzman RJ, Prestrud AA, Brodsky I. High-dose cyclophosphamide for severe, refractory myasthenia gravis. Journal of Neurology, Neurosurgery & Psychiatry 2004; 75:789-791.
111. Dey DD, Schwartzman RJ. Incidence of disabling neurological complications in patients with CRPS of over ten years duration. (submitted to Journal of Pain and Symptom Management 2004)
112. Goldberg ME, Domsky R, MD, Scaringe D, Hirsh R, Dotson J, Sharaf I, Schwartzman RJ. Multi-day low dose ketamine infusion for the treatment of complex regional pain syndrome. Submitted to Pain Physician 2004.
113. Kiefer RT, Rohr P, Ploppa A, Nohe B, Dieterich HJ, Grothusen J, Altemeyer KH, Schwartzman RJ. Effects of subanesthetic S(+)-ketamine infusions on pain relief and thermo- and mechanosensory thresholds in severe complex regional pain syndrome (CRPS) refractory to conventional therapy. Submitted to Journal of Pain and Symptom Management 2004. |