What is FNAB? Fine Needle Aspiration Biopsy (FNAB) is a quick and reliable method of sampling a palpable mass (lump). It is a biopsy technique that uses a small needle to obtain a sample of cells from the mass for examination with a microscope.. The aspiration biopsy is a simple procedure requiring an appointment of approximately 30-45 minutes and no hospitalization. Why do an FNAB? The purpose of performing an FNAB is to determine the reason for your lump. In approximately 95% of the cases, FNAB can determine the specific cause and in the remaining 5%, we will be able to provide useful information to your doctor. What is the procedure like? The procedure is relatively simple and fast. We will start by asking you a few questions about your lump. Your answers to these questions as well as a review of other available data such as x-rays will help to establish a diagnosis. We will then examine the lump to determine its physical characteristics. Next, the skin over the lump will be numbed through the use of an ice pack or by injecting a few drops of a local anesthetic. The actual biopsy time is brief lasting only a few seconds. The biopsy needle is considerably smaller than that used to draw blood from your arm. After the needle is introduced into the lump, suction is applied for a few seconds there may be brief discomfort.. The biopsy is over. Once the procedure is finished, you are free to resume your regular activities. What are the possible complications? When performed by an experienced person, the procedure is virtually free of complications. The most common complication is local bruising, which occurs in only a small fraction of patients. How to contact Faculty? Lorenzo M. Galindo, M.D. Director, Cytodiagnostic Center Fernando Garcia, M.D. Please report to the Fine Needle Aspiration Clinic for your scheduled appointment. The clinic is located on the 15th floor of Hahnemann Hospital South Tower. Broad and Vine Street, Philadelphia, Pa.