Image of Graziano, Alessandro

Alessandro Graziano, PhD

Assistant Professor

  • Department:Pharmacology & Physiology
  • Education: PhD, University of Rome La Sapienza, Italy

The main focus of Dr. Graziano's research is understanding the mechanisms of central nervous system plasticity that cause the emergence and maintenance of central pain after spinal cord injury or other chronic pain conditions. The conscious sensation of pain depends on specific patterns of synchronous activity of cortical and thalamic neuronal groups. Dr. Graziano is interested in identifying molecular markers for cell types specifically involved in pain-related activity in the thalamocortical circuitry, and using these molecules to modulate the excitability of cortical and thalamic neurons, either pharmacologically or using newly developed techniques called "optogenetics," in order to modify their pattern of activation and hence control pain sensation.

Academic Location

Department of Pharmacology & Physiology
245 North 15th Street
Mail Stop #488
Philadelphia, PA 19102
Phone: 215-762-7669
Fax: 215-762-2299

Additional Information

Lab location: New College Building, Room 8217

Email Dr. Graziano

Related Pages

Pharmacology & Physiology

Biomedical Graduate Studies

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