During the past two decades, Dr. Katsetos' research has focused on cellular aspects of growth and differentiation of human embryonal tumors of the nervous system (medulloblastomas, neuroblastomas and retinoblastomas) and on molecular aspects of viral neuro-oncogenesis. Currently, Dr. Katsetos' research focuses primarily on alterations of the microtubule cytoskeleton in human brain tumors with emphasis on glioblastomas.
Selected Publications (See all Dr. Katsetos' publications in PubMed, "Katsetos CD".)
"Tubulins as therapeutic targets in cancer: from bench to bedside."
Katsetos, C.D. and Dráber, P.
Current Pharmaceutical Design, 18(19):2778-2792 (2012)
"Overexpression of gamma-tubulin in non-small cell lung cancer."
Maounis, N.F., Dráberová, E., Mahera, E., Chorti, M., Caracciolo, V. , Sulimenko, T., Riga, D., Trakas, N., Emmanouilidou, A., Giordano, A., Dráber, P., and Katsetos, C.D.
Histology and Histopathology 27:1183-119 (2012)
"Nuclear gamma-tubulin associates with nucleoli and interacts with tumor suppressor protein C53."
Horejší, B., Vinopal, S., Sládková, V., Dráberová, E., Sulimenko, V., Sulimenko, T., Vosecká, V., Philimonenko, A., Hozák, P., Katsetos, C.D., and Dráber, P.
Journal of Cellular Physiology, 227(1):367-382 (2012) doi: 10.1002/jcp.22772
"Microtubule severing ATPase spastin in glioblastoma multiforme: Increased expression in human glioblastoma cell lines and roles in cell motility and proliferation."
Dráberová, E., Vinopal, S., Morfini, G., Liu, P.S., Sládková, V., Sulimenko, T., Burns, M.R., Solowska, J., Kulandeival, K., de Chadarevian, J.-P., Legido, A., Mörk, S.J., Jurácek, J., Baas, P.W., Dráber, P., and Katsetos, C.D.
Journal of Neuropathology & Experimental Neurology, 70(9): 811-826 (2011)
"Targeting betaIII-tubulin in glioblastoma multiforme: From cell biology and histopathology to cancer therapeutics."
Katsetos, C.D., Dráber, P., and Kavallaris, M.
Anti-Cancer Agents in Medicinal Chemistry, 11(8):719-728 (2011)
"Differential expression and cellular distribution of gamma-tubulin and betaIII-tubulin in medulloblastomas and human medulloblastoma cell lines."
Caracciolo, V., D'Agostino, L., Dráberová, E., Sladková, V., Crozier-Fitzgerald, C., Agamanolis, D.P., de Chadarévian, J.-P., Legido, A., Giordano, A., Dráber, P., and Katsetos, C.D.
Journal of Cellular Physiology, 223:519-529 (2010)
"Tubulin targets in the pathobiology and treatment of glioblastoma multiforme. I. Class III beta tubulin isotype."
Katsetos, C.D., Dráberová, E., Legido, A., Dumontet, C., and Dráber, P.
Journal of Cellular Physiology, 221:505-513 (2009)
"Tubulin targets in the pathobiology and treatment of glioblastoma multiforme. II. gamma-Tubulin."
Katsetos, C.D., Dráberová, E., Legido, A., and Dráber, P.
Journal of Cellular Physiology, 221:514-520 (2009)
"Class III beta-tubulin is constitutively co-expressed with glial fibrillary acidic protein and nestin in midgestational human fetal astrocytes: Implications for phenotypic identity."
Dráberová, E., Del Valle, L., Gordon, J., Marková, V., Smejkalová, B., Bertrand, L,, de Chadarévian, J.-P., Agamanolis, D.P., Legido, A., Khalili, K., Dráber, P., and Katsetos, C.D.
Journal of Neuropathology & Experimental Neurology, 67: 341-354 (2008)
"Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells."
Katsetos, C.D., Dráberová, E., Smejkalová, B., Reddy, G., Bertrand, L., de Chadarévian, J.-P., Legido, A., Nissanov, J., Baas, P.W., and Dráber, P.
Neurochemical Research 32:1387-1398 (2007)
"Altered cellular distribution and subcellular sorting of gamma-tubulin in astrocytic gliomas and human glioblastoma cell lines."
Katsetos, C.D., Reddy, G., Dráberová, E., Smejkalova, B., Del Valle, L., Ashraf, Q., Tadevosyan, A., Yelin, K., Maraziotis, T., Mishra, O.P., Nissanov, J., Mörk, S., Legido, A., Baas, P.W., de Chadarévian, J.-P., and Dráber, P.
Journal of Neuropathology & Experimental Neurology, 65:465-477 (2006)
"Class III beta-tubulin in human development and cancer."
Katsetos, C.D., Herman, M.M., and Mörk, S.J.
Cell Motility and the Cytoskeleton, 55:77-96 (2003)
"Class III beta-tubulin isotype: A key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology."
Katsetos, C.D., Legido, A., Perentes, E., and Mörk, S.J.
Journal of Child Neurology, 18:851-866 (2003)
"On the neuronal/neuroblastic nature of medulloblastomas: A tribute to Pio del Rio Hortega and Moises Polak."
Katsetos, C.D., Del Valle, L, Legido, A., de Chadarevian, J.-P., Perentes, E., and Mörk, S.J.
Acta Neuropathologica (Berlin) 105:1-13 (2003)
"Localization of neuronal class III beta-tubulin in oligodendrogliomas. Comparison with Ki-67 proliferative index and 1p/19q status."
Katsetos, C.D., Del Valle, L., Geddes, J.F., Aldape, K., Boyd, J.C., Legido, A., Khalili, K., Perentes, E., and Mörk, S.J.
Journal of Neuropathology & Experimental Neurology, 61:307-320 (2002)
"Aberrant localization of the neuronal class III beta-tubulin in astrocytomas: A marker for anaplastic potential."
Katsetos, C.D., Del Valle, L., Geddes, J.F., Assimakopoulou, M., Legido, A., Boyd, J.C., Balin, B.J., Parikh, N.A., de Chadarevian, J.-P., Maraziotis, T., Varakis, J.N., Matsas, R., Spano, A., Frankfurter, A., Herman, M.M., and Khalili, K.
Archives of Pathology & Laboratory Medicine, 125: 613-624 (2001)
"Differential distribution of the neuron-associated class III beta-tubulin in neuroendocrine lung tumors."
Katsetos, C.D., Kontogeorgos, G., Geddes, J.F., Herman, M.M., Tsimara-Papastamatiou, H., Yu, Y., Sakkas, L.I., Tsokos, M., Patchefsky, A.S., Ehya, H., Cooper, H.S., Provencio, J., Spano, A.J., and Frankfurter, A.
Archives of Pathology & Laboratory Medicine, 124:535-544 (2000)
"Class III beta-tubulin isotype (beta III) in the adrenal medulla: III. Differential expression of neuronal and glial antigens identifies two distinct populations of neuronal and glial-like (sustentacular) cells in the PC12 rat pheochromocytoma cell line maintained in a Gelfoam matrix system."
Katsetos, C.D., Herman, M.M., Balin, B.J., Vinores, S.A., Hessler, R.B., Arking, E.J., Karkavelas, G., and Frankfurter A.
The Anatomical Record, 250:351-365 (1998)
"Class III beta-tubulin isotype (beta III) in the adrenal medulla: I. Localization in the developing human adrenal medulla."
Katsetos, C.D., Karkavelas, G., Herman, M.M., Vinores, S.A., Provencio, J., Spano, A.J., and Frankfurter A.
The Anatomical Record, 250:335-343 (1998)
"Differential localization of class III, beta-tubulin isotype and calbindin-D28k defines distinct neuronal types in the developing human cerebellar cortex."
Katsetos, C.D., Frankfurter, A., Christakos, S., Mancall, E.L., Vlachos, I., and Urich, H.
Journal of Neuropathology & Experimental Neurology, 52:655-666 (1993) |