Biography
Dr. Goldman received her PhD in Physical Anthropology from the City University of New York in 2001 (as part of the New York Consortium of Evolutionary Primatology (NYCEP) Graduate Program in Anthropology).
She joined the faculty of Drexel University in 2002 as an educator, but also maintains an active research program in bone biology.
Teaching
Goldman teaches gross anatomy and microanatomy to first year medical students, as part of Drexel's PIL and IFM programs, and is co-director of the PIL anatomy course.
She is also developing web-based microanatomy resources for students using virtual slide technologies.
She participates in an advanced anatomy course for Orthopedic Surgery Residents, and teaches in Human Osteology and Forensic Anthropology courses in one of DUCOM’s master’s programs.
In the past, she has taught at the undergraduate level in Physical Anthropology, including courses such as human osteology, forensic anthropology, and comparative primate anatomy.
Research Interests
Goldman’s research in bone biology aims to improve our understanding how the size and shape of whole bones, as well as the distribution, quantity and quality of the mineralized tissue that forms the bone, reflect both constraints of skeletal growth and development, and responsiveness to mechanical loading during life.
Her research has focused on examining changes in bone quality with age in humans, including selected material (i.e. histological composition) and structural (i.e. geometric shape) properties of bone.
This research has applications to both the study of age related bone diseases such as osteoporosis, as well as to the reconstruction of health and activities of past populations (through the study of archaeological skeletal remains).
Her current research activities include studies of bone growth and development in order to better understand how these processes influence the attainment of adult bone morphology and quality at macrostructural, microstructural and nanostructural length scales, and how changes in bone structure affect fracture risk as adults and with aging.
In 2004, Goldman established the Bone Biology Laboratory, which is dedicated to the study of bone quality, structure and adaptation during growth, aging and disease. The laboratory is located at Drexel's Queen Lane campus, established with support from the Department of Orthopedic Surgery. The facility will provide Drexel students and residents new opportunities to participate in bone biology research, as well as to foster interdisciplinary research in musculoskeletal biology between Basic Science, Clinical Orthopedics and Engineering disciplines.
Selected Publications
Goldman, H. M., Kindsvater, J. & Bromage, T. G. (1999) Correlative Light and Backscattered Electron Microscopy of Bone. Part I: Specimen Preparation Methods. Scanning 21(1): 40-43.
Goldman, H. M., Bromage, T. G., Blayvas, A., Boyde, A., Howell, P. & Clement, J.G. (2000) Correlative Light and Backscattered Electron Microscopy of Human Bone. Part II: Automated Image Analysis. Scanning 22(6): 337-344.
Goldman, H.M., Bromage, T.G., Thomas, C.D.L. and Clement, J.G. (2003) Preferred Collagen Fiber Orientation at the Human Mid-Shaft Femur. The Anatomical Record.272A: 434-445.
Goldman, H.M., Bromage, T.G., Boyde, A., Thomas, C.D.L. and Clement, J.G. (2003) Intrapopulation Variability in Mineralization Density at the Human Femoral Mid-Shaft. Journal of Anatomy 203:243-255.
Bromage, T.G., Goldman, H.M., McFarlin, S., Warshaw, J. and Boyde, A. (2003). Circularly polarized light investigations of collagen fiber orientation in bone. The New Anatomist.274B:157-168.
Goldman, H.M., Clement, J.G., Thomas, C.D.L. and Bromage, T.G. (2005) Relationships among microstructural properties of bone at the human mid-shaft femur. Journal of Anatomy. 206:127-139.
Price, C., Herman, B.C., Lufkin, T., Goldman, H.M. and Jepsen, K.J. (2005) Genetic Variation in Bone Growth Patterns Defines Adult Mouse Bone Fragility. Journal of Bone and Mineral Research 20(11):1983-91.
Goldman, H.M., S.M. McFarlin, D.M.L. Cooper, C.D. Thomas and J. G. Clement (2009) Ontogenetic patterning of cortical bone microstructure and geometry. The Anatomical Record, 292:48–64.
Bromage, T.G., Lacruz, R.S., Hogg, R., Goldman, H.M., McFarlin, S.C., Warshaw, J., Dirks, W., Perez-Ochoa, A., Smolyar, I., Enlow, D.H. and Boyde, A. (in press) Lamellar bone reconciles enamel rhythms, body size, and organismal life history. Calcified Tissue International.
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