Swarthmore College, B.A., Biochemistry, 1986
Harvard University, 1987
University of Pennsylvania, Ph.D., Pharmacological Sciences (Neuropsychopharmacology), 1993
Animal Models of Human Conditions
Course Director: IFM Medical Neuroscience
My research interests forge an integrated linkage between the fields of developmental molecular neurobiology, rehabilitation therapy, and behavioral pharmacology. I serve as the Scientific Director for the Behavioral Core Facility of The Spinal Cord Research Center. My primary research in collaboration with Drs. Itzhak Fischer, Karen Moxon, and John Houle is in behavioral assessment of recovery of function from spinal cord injury. We are examining the interaction between pharmacologic stimulation, rehabilitation training, and cellular transplants as combined intervention strategies to improve recovery of function in our rat spinal injury models. My secondary area of research involves collaboration with Drs. Barry Waterhouse, Brian Wigdahl, Wen-Jun Gao, and Brian Clark to study the effects of Ritalin on the neurobiology of sustained attention in rats in a model of AIDS-related dementia. Through these studies we are examining cortical mechanisms underlying cognitive enhancement and attention processing.
MMS Candidate 2012-present
Thesis: Adrenergic pharmacology of sustained attention.
"Neurobehavioral assessments of spinal cord injury"
Shumsky, J.S.; Houle, J.D.
(2012) In: (Chen, J.; Xu, X.M.; Xu, Z.C.; Zhang, J.H., eds.) Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments, Springer-Verlag: New York.
"Amphetamine enhanced motor training following cervical contusion injury"
Krisa, L.; Frederick, K.L.; Canver, J.C.; Stackhouse, S.K.; Shumsky, J.S.; Murray, M.
(2012) J. Neurotrauma 29:971-989. Epub 2011, Sept 19.
"Experimental strategies for investigating psychostimulant drug actions and prefrontal cortical function in ADHD and related attention disorders"
Agster, K.L.; Clark, B.D.; Gao, W-J.; Shumsky, J.S.; Wang, H-X.; Berridge, C.W.; Waterhouse, B.D.
(2011) In: (Lin, R. ed.) Anat Record. 294: 1698-1712.
"Differential sensitivity to psychostimulants across prefrontal cognitive tasks: Differential involvement of noradrenergic a1- vs. a2-receptors"
Berridge, C.W.; Shumsky, J.S.; Andrzejewski, M.E.; McGaughy, J.A.; Spencer, R.C.; Devilbiss, D.M.; Waterhouse, B.D.
(2011) Biol Psychiatr 71:467-73. Epub 2011, Sept 2.
"Functional role of exercise-induced, cortical plasticity in the sensorimotor cortex after spinal cord injury"
Moxon, K.A.; Kao, T.; Shumsky, J.S.; Knudsen, E.; Murray, M.
(2011) J Neurophys 106:2662-74. Epub 2011, Aug 24.
"5-HT precursor loading enhances motor function after spinal cord contusion in adult rats"
Hayashi, Y.; Jacob-Vadakot, S.; Nothias, J.-M.; McBride, S.; Olexa, R.; Murray, M.; Simansky, K.; Shumsky, J.S.
(2010) Exp Neurol 221:68-78.