Drexel University College of Medicine

Dr. Nancy MacGarvey is an assistant professor in the Division of Pulmonary and Critical Care Medicine. She is board certified by the American Board of Internal Medicine in internal medicine, pulmonary medicine, and critical care medicine. Her research interest has focused on the mechanisms of mitochondrial biogenesis during Staphylococcus aureus sepsis. Her other clinical interests include pulmonary hypertension, lung cancer, and general pulmonary medicine.

Dr. MacGarvey sees patients in Center City Philadelphia.

Memberships

• American Thoracic Society (2007 - present)
• American College of Chest Physicians (2007 - present)
• American Medical Association (2004 - present)

Selected Publications

"Activation of mitochondrial biogenesis by HO-1 mediated Nrf2 induction rescues mice from lethal S. aureus sepsis."
N.C. MacGarvey, H.B. Suliman, R.R. Bartz, P. Fu, C.M. Withers, K. Welty-Wolf, T.E. Sweeney, and C.A. Piantadosi
American Journal of Respiratory and Critical Care Medicine (2012)

"Heme oxygenase-1 couples activation of Mitochondrial Biogenesis to Anti-inflammatory Cytokine Expression."
C.A. Piantadosi, C.M. Withers, R.R. Bartz, N.C. MacGarvey, P. Fu, T.M. Sweeney, K.E. Welty-Wolf, and H.B. Suliman
Journal of Biological Chemistry, 286(18): 16374-85 (2011)

"Staphylococcus Aureus Sepsis and Mitochondrial Accrual of the 8-oxoguanine DNA glycosylase DNA Repair Enzyme in Mice."
R.R. Bartz, H.B. Suliman, P. Fu, K. Welty-Wolf, M.S. Carraway, N.C. MacGarvey, C.M. Withers, T.E. Sweeney, and C.A. Piantadosi
American Journal of Respiratory and Critical Care Medicine, 183(2): 226-33 (2011)

Selected Abstracts

"The HO/CO system promotes hepatic mitochondrial biogenesis during Staphylococcus Aureus sepsis."
N.C. MacGarvey, M.D., H.B. Suliman, Ph.D., and C.A. Piantadosi, M.D.
Selected for poster discussion session at ATS (2010)

• Pulmonary Medicine
• Critical Care

• Critical care
• Endobronchial ultrasound
• Lung cancer
• Lung disease
• Pulmonary hypertension
• Respiratory medicine

• Internal Medicine - University of Texas – Southwestern, Dallas, TX (2004–2005)

• Internal Medicine - University of Texas - Southwestern, Dallas, TX (2005-2007)

• Pulmonary and Critical Care - Duke University Medical Center, Durham, NC (2007–2010)

Selected Poster Presentations

"The HO/CO system promotes hepatic mitochondrial biogenesis during Staphylococcus Aureus sepsis"
N. MacGarvey, M.D., H.B. Suliman, Ph.D., and C.A. Piantadosi, M.D.

Selected Oral Presentations

"The HO/CO system promotes hepatic mitochondrial biogenesis during Staphylococcus Aureus sepsis."
Duke University Research Conference (2010)

"Is there a role for carbon monoxide in sepsis."
Duke University Research Conference (2009)

"Clostridium difficile: management of refractory cases."
Citywide Infectious Disease Conference (2003)