Since 1987, Dr. Joshi has taught undergraduate, postgraduate and doctoral students and trained doctoral and post-doctoral fellows in research. He has been mentoring graduates and medical students, who now have successful careers in medicine, academia and the pharmaceutical industry.
Research Fellows with Dr. Joshi: Bhaswati Sen, Adam Yost, Nachiket Vaze, Tarika Chawla, Kevin Diaz, Christina Sze, Rebecca Hasley.
Subjects Taught: Medical Microbiology, Pathology, Parasitology, Communicable Diseases, Hospital-Acquired Infections and Infection Control Methods.
Visiting Department Faculty Fellow: University of Rochester Medical Center, Rochester, New York
Sr. Research Fellowship & Adjunct Faculty: Thomas Jefferson University Medical College, Philadelphia, PA
Certification: Infection Control, State of New York
Board Eligible: For American Board of Medical Microbiology
Postgraduate Training (Masters and doctoral): Medical Microbiology, and Biochemistry & Cell Biology
Medical Training: Medical Microbiology, as well as Family Physician. Practicing physician since 1986
Dr. Joshi’s research areas are related to bacterial pathogenesis and biofilms. He has extensive experience in the areas of antimicrobial resistance, nosocomial infection, and molecular and clinical epidemiology, and drug development. He is also working in the area of host cellular responses (with a special focus on apoptosis and mediation of NFkB and caspases) to bacterial pathogens and/or their virulence products. Joshi has developed several in vitro and in vivo assays, and has expertise in immunocytochemical (ICC) and immunohistochemical (IHC) detection systems and microscopies. He has initiated Surgical Infections Research (SIR) program at this institute, with a special emphasis to multi-drug resistant (MDR)- Acinetobacter and MRSA infection. The major current topics of research in Dr. Joshi's lab are:
- Carbapenem resistant-Acinetobacter baumannii: antibiotic resistance mechanisms, and pathogenesis.
- Antimicrobial and anti-biofilm strategies: using atmospheric non-thermal plasma, novel antimicrobial sustained release, antimicrobial augmentation.
- Molecualr diagnostics strategies for multidrug-resistant A. baumannii, C. difficile and MRSA.
- Botulinum toxin: host responses, vaccine development, novel diagnostic techniques.
- Novel beta-lactamase inhibitors with carbapenems against complicated intra-abdominal infection.
- Clinical response and efficacy of novel beta-lactamase inhibitor in urinary tract infection therapeutic regime.
- Effect of novel antimicrobial solution and its clinical efficacy in the management of atopic dermatitis (being submitted).
(See all Suresh Joshi's publications in PubMed.)
"OXA-mediated carbapenem resistance is predominant in Acinetobacter baumannii isolated from hospitalized patients from Philadelphia"
Sen B, Joshi SG.
(Under review, 2013)
"Antimicrobial properties of water treated by non-equilibrium plasma”
Kojtari A, Ercan U, Smith J, Friedman G, Sensenig R, Tyagi S, Joshi SG, Ji H, Brooks AD.
(Under review, 2013)
"Multidrug-resistant-biofilm inhibitory efficacies of non-thermal plasma treated novel solutions”
Ercan UK, Joshi SS, Yost A, Gogotsi N, O'Toole S, Paff M, Melchior E, Joshi SG.
(Under review, 2013)
"Antimicrobial efficacy and wound healing property of a topical ointment containing nitric oxide-loaded Zeolite”
Neidrauer M, Ercan UK, Bhattachryya A, Samuels J, Sedlak J, Trikha R, Barbee KA, Weingarten MS, Joshi SG.
Journal of Medical Microbiology 2013 Nov 6 (Epub; ahead of print)
"Microbial and cellular responses to nonthermal plasma-treated alginate wound dressing: control of multidrug-resistant pathogens”
Poor AE, Ercan UK, Yost A, Brooks AD, Joshi SG.
Surgical Infections 2013 (In Press)
"The presence and impact of biofilm-producing staphylococci in atopic dermatitis”
Allen HB, Vaze NS, Choi C, Hailu T, Cusack CA, Joshi SG.
JAMA Dermatology, 2013 (In Press)
"Acinetobacter: An emerging pathogenic threat to public health"
Joshi SG and Litake GM.
World Journal of Clinical Infectious Diseases, 3(3): 25-36 (2013)
"Patient demographics and characteristics of infection with carbapenem-resistant Acinetobacter baumannii in a teaching hospital from the United States"
Vaze ND, Emery CL, Hamilton RJ, Brooks AD, and Joshi SG
Advances in Infectious Diseases, 3(1):10-16 (2013)
"Nonequilibrium plasma-activated antimicrobial solutions are broad-spectrum and retain their efficacies for extended period of time"
Ercan UK, Wang H, Ji H, Fridman G, Brooks AD, and Joshi SG
Plasma Processes and Polymers, 10(6): 544-555 (2013)
"Institutional MRSA screening practice and policies"
Joshi SG, Hamilton RJ, Emery CL, Brooks AD
American Journal of Infection Control, 40(9): 898-901 (2012).
"An analysis of the mechanisms that underlie absorption of botulinum toxin by the inhalation route"
Al-Saleem FH, Ancharski DM, Joshi SG, Elias MD, Singh A, Nasser Z, and Simposn LL
Infection and Immunity,80(12): 4133-4142 (2012) .
"Porcine intact and wounded skin responses to FE-DBD atmospheric non-thermal plasma"
Wu AS, Kalghatgi S, Dobrynin D, Sensenig R, Podolsky E, Dulaimi E, Paff M, Garcia K, Wasko K, Fridman G, Balasubramanian M, Ownbey R, Barbee KA, Fridman A, Friedman G, Joshi SG, and Brooks AD
Journal of Surgical Research, 179(1): e1-e12 (2013).
"Detection of biologically active botulinum neurotoxin-A from serum using high throughput FRET-assay"
Journal of Pharmacological & Toxicological Methods, 65(1): 8-12 (2011).
"Occurance of and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) at a teaching hospital in Philadelphia"
Gomes S, Altafi S, Garcia K, Emery C, Hamilton R, Brooks AD, and Joshi SG
American Journal of Infection Control, 40(4): 381-383 (2011).
"Isolation of Burkholderia cenocepacia J2315 from non-cystic fibrosis pediatric patients from India"
Satpute MG, Telang NV, Dhakephalkar PK, Niphadkar KB, and Joshi SG
American Journal of Infection Control, 39(4):e21-23 (2011)
"Fulminating septicemia due to persistent pan-resistant community-acquired MBL (IMP1)-positive Acinetobacter baumannii"
Telang NV, Satpute MG, Dhakephalkar PK, Niphadkar KB, and Joshi SG
Indian Journal of Pathology and Microbiology, 54(1): 180-182 (2011)
"Modulation of botulinum toxin-induced changes in neuromuscular function with antibodies directed against recombinant polypeptides or fragments"
Joshi SG, Elias MD, Singh AK, Al-Saleem FH, Ancharski DM, Nasser Z, Takahashi T, and Simpson LL
Neuroscience, 179: 208-222 (2011)
"Non-thermal dielectric-barrier discharge (DBD) plasma-induced inactivation involves oxidative-DNA damage and membrane lipid peroxidation in Escherichia coli"
Joshi SG, Cooper M, Yost A, Paff M, Ercan UK, Fridman G, Friedman G, Fridman A, and Brooks AD
Antimicrobial Agents and Chemotherapy, 52: 1053-1062 (2011)
"Live pig skin tissue and wound toxicity of cold plasma treatment"
Dobrynin D, Wu A, Kalghatgi S, Park S, Shainsky N, Wasko K, Dulaimi E, Ownbey R, Sensenig R, Joshi SG, and Brooks AD
Plasma Medicine, 1(1): 93-108 (2010)
"Biological responses of Bacillus stratosphericus to floating electrode-dielectric barrier discharge plasma treatment"
Cooper M, Fridman G, Fridman A, and Joshi SG
Journal of Applied Microbiology, 109: 2039-2048 (2010)
"Control of methicillin-resistant Staphylococcus aureus (MRSA) in planktonic form and biofilms: a biocidal efficacy study of non-thermal DBD-plasma"
Joshi SG, Paff M, Friedman G, Fridman G, Fridman A, and Brooks AD
American Journal of Infection Control, 38: 293-301 (2010)
"An increased incidence of biofilm-producing MDR methicillin-resistant Staphylococcus aureus in a tertiary care hospital from India: Two years study"
Telang NV, Satpute MG, Niphadkar KB, and Joshi SG
American Journal of Infection Control, 38: 165-166 (2010)
"PER-1 type-extended-spectrum-beta-lactamase-producing Acinetobacter baumannii clinical isolates from India"
Litake GM, Ghole VS, Niphadkar KB, and Joshi SG
International Journal of Antimicrobial Agents, 34: 280-283 (2009)
"Localization of the sites and characterization of the mechanisms by which anti-light chain antibodies neutralize the actions of the botulinum holotoxin"
Takahashi T, Joshi SG, Al-Saleem FH, Ancharski D, Singh AK, Nisser Z, and Simpson LL
Vaccine, 27: 2616-2624 (2009)
"The role of systemic handling in the pathophysiologic actions of botulinum toxin"
Al-Saleem FH, Ancharski DM, Ravichandran E, Joshi SG, Singh AK, Gong Y, and Simpson LL
Journal of Pharmacology & Experimental Therapeutics, 326: 856-863 (2008)
- A.J. Drexel Plasma Institute, Drexel University, Philadelphia
- Center for Botulism and Biodefense Research (CBBR), Thomas Jefferson University
- Institute of Molecular Medicine and Infectious Diseases, Dexel University College of Medicine
- School of Biomedical Engineering, Science and Health Systems, Drexel University
- KEM Hospital & Research Center, Pune, and University of Pune, Pune (India)
- Hadassah Hebrew University Medical Center, Jerusalem (Israel)
- UNESCO-ASM Visiting Resource Person, 2002, 2004
- National Judge & Evaluator for Annual Biomed Research Conf for Minority Students (ABRCMS), 2008, 2009, 2010
- International Mentoring Program & Minority Mentoring Program, American Society for Microbiology, and Infect Dis Society of America.
- Editorial Board Service to BMC Infectious Diseases (Associate Editor); Surgery: Current Research; World Journal of Clinical Infectious Diseases; Afr Journal of Infectious Diseases, International Journal of Bacteriology, and Journal of Drug Development.