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Faculty

Queen Lane Campus

Carol Artlett

Role of 3-deoxyglucosone in mediating inflammation in diabetes and autoimmunity and the role of the inflammasome in systemic sclerosis

Lawrence W. Bergman

Malarial invasion mechanisms and cellular gene expression patterns during infection
Elizabeth Blankenhorn Genetic foundations for inherited susceptibility to autoimmune diseases, including diabetes and multiple sclerosis
Alina Boesteanu Migration of dendritic cells to the lung after influenza virus infection, and the role of costimulatory molecules in the primary, secondary and memory immune responses to influenza virus
James Burns Development of protective immunity against blood-stage malaria induced by immunization with defined subunit vaccines
Thomas Edlind Molecular mechanisms of antifungal action, resistance, and toxicity
Santosh Katiyar Molecular mechanisms of antifungal resistance
Peter Katsikis Roles of cytokines, T cells, and apoptosis in autoimmunity and anti-viral immune responses
Simon Knight Drug resistance mechanisms and iron acquisition processes in the Candida genus of opportunistic fungal pathogens
Sandhya Kortagere

Development and application of computational tools in drug discovery

Kirsten Larson Course director of medical immunology and medical genetics, and development and implementation of both team-taught courses in our medical school curricula
Yvonne Mueller Function of virus-specific cytotoxic CD8+ T cells
Richard Rest Molecular and cellular mechanisms of the pathogenesis of Neisseria gonorrhoeae, Neisseria meningitidis, and Bacillus anthracis
Donna Russo Director of the medical school curriculum, Interdisciplinary Foundations of Medicine, as well as department course director for Medical Microbiology
Sandra Urdaneta-Hartmann Microbicide development, mother-to-child-transmission of HIV-1 through breast milk, sexually transmitted infections, women’s health
Akhil Vaidya Understanding basic molecular functioning of malaria parasites with a view to develop new antimalarial drugs

Center City Campus

Michael Bouchard Liver Cancer, hepatocyte transformation, calcium signaling, apoptosis, cell proliferation, alcohol, novel liver models (Secondary Appointment)

Richard Huneke

Utilization and overview of animal models in biological research
Jeffrey Jacobson Infectious diseases, HIV, immunology (Secondary Appointment)
Stephen Jennings Optimal protection from HSV-1 infection provided by interactions between innate and acquired immune responses
Suresh Joshi Surgical and nosocomial infections, bacterial pathogenesis, antimicrobial resistance, novel agents
Fred Krebs HIV-1 immunopathogensis and neuropathogenesis, development of microbicidal agents
Michelle Kutzler Translational research in vaccinology, immunology and infectious disease (Secondary Appointment)

Julio Martín-García

HIV-1 envelope-mediated fusion and entry, HIV neurotropism and neuropathogenesis

Olimpia Meucci NeuroAIDS (Secondary Appointment)
Sonia Navas-Martín Molecular pathogenesis and evolution of RNA viruses. Animal models for viral infectious diseases.
Michael Nonnemacher Impact of genetic variation and drugs of abuse on HIV-1 and SIV replication and pathogenesis
Shendra Passic Microbicide development, HIV-1 transmission, HIV-1 immunopathogenesis and neuropathogenesis
Edward Schulman Allergies, asthma, interstitial lung diseases (Secondary Appointment)

Laura Steel

Development of RNAi-based therapies for hepatitis B virus (HBV)
Brian Wigdahl

Immunopathogenesis and neuropathogenesis of HIV-1 and HTLV-I infection, transcriptional regulation of retroviral expression, viral sequence diversity and correlations to disease, development of microbicidal agents

Doylestown Campus
Drexel Institute for Biotechnology and Virology Research

Timothy Block

Molecular mechanisms of viral persistence and development of therapeutic strategies for hepatitis B virus (HBV) and herpes simplex virus (HSV)
Jinhong Chang  
Maryann Comunale  
Haitao Guo Molecular pathway of HBV cccDNA formation and cccDNA regulation by viral and cellular factors; Development of in vitro assay systems for discovery of novel antiviral drugs.
Ju-Tao Guo  
Pooja Jain Dendritic cells in autoimmune and neuroinflammatory disease
Zafar K. Khan Animal modeling of microbial infections and neuroinflammation

Xuanyong Lu

Cellular susceptibility to hepatitis B (HBV) infection; developing strategies to control cancer cell growth through silencing of overexpressed apoptosis inhibitors
Anand Mehta Development of new hepatitis B (HBV) therapeutics; identification of early markers of liver cancer
Scott Millhouse The host-pathogen relationship and its importance to lytic and latent phases of the herpes virus life-cycle
Brad Nefsky  

Pamela Norton

Development of novel antiviral drugs for use against hepatitis B virus (HBV) infection; host cell defenses against HBV infection
David Ren  
Patrick Romano  

Ying-Hsiu Su

Understanding interactions between herpes simplex virus type 1 (HSV-1) and neurons during viral latency and reactivation; using nucleic acids in urine as diagnostic markers of cancer

Allegheny General Hospital
Allegheny-Singer Research Institute
Center for Genomic Sciences
Pittsburgh, PA

Farrel Joel Buchinsky

Determining genetic susceptibility of recurrent respiratory papillomatosis
Garth D. Ehrlich

Molecular pathogenesis of chronic infectious diseases

Fen Z. Hu Bacterial Biofilm Pathogenesis
Sandeep Kathju Gene regulation during scarless wound healing

James Christopher Post

Role of biofilms in chronic human infections using otitis media as a model. Genetics of human performance, scarless wound healing.