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NIMH NeuroAIDS Training Grant

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Faculty

Queen Lane Campus

Faculty

Research

Carol Artlett

Role of 3-deoxyglucosone in mediating inflammation in diabetes and autoimmunity and the role of the inflammasome in systemic sclerosis.

Lawrence W. Bergman

Malarial invasion mechanisms and cellular gene expression patterns during infection.

Elizabeth Blankenhorn

Genetic foundations for inherited susceptibility to autoimmune diseases, including diabetes, scleroderma and multiple sclerosis. Impact of genetics on wound healing and susceptibility to viral infection.

Alina Boesteanu

Lung immunopathology induced by influenza virus infection. Identification of therapeutic targets for reducing viral load and lung inflammation.

James Burns

Development of protective immunity against blood-stage malaria induced by immunization with defined subunit vaccines.

Thomas Daly  

Santosh Katiyar

Molecular mechanisms of antifungal resistance.

Peter Katsikis

Roles of cytokines, T cells, and apoptosis in autoimmunity and anti-viral immune responses.

Sandhya Kortagere

Designing small molecule modulators of therapeutically relevant protein targets using structure based drug design methods.

Kirsten Larson

Course director of medical immunology and medical genetics, and development and implementation of both team-taught courses in our medical school curricula.

Michael Mather

Physiology of malaria parasites

Joanne Morrisey  

Yvonne Mueller

Function of virus-specific cytotoxic CD8+ T cells.

Shira Ninio

Intracellular bacterial pathogens, host-pathogen interaction, Legionella pneumophila pathogenesis

Richard Rest

Molecular and cellular mechanisms of the pathogenesis of Neisseria gonorrhoeae, Neisseria meningitidis, and Bacillus anthracis.

Donna Russo

Director of the medical school curriculum, Interdisciplinary Foundations of Medicine, as well as department course director for Medical Microbiology.

Akhil Vaidya

Understanding basic molecular functioning of malaria parasites with a view to develop new antimalarial drugs.

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Center City Campus

Faculty

Research

Michael Bouchard

Liver cancer, hepatocyte transformation, calcium signaling, apoptosis, cell proliferation, alcohol, novel liver models (secondary appointment).

Richard Huneke

Utilization and overview of animal models in biological research.

Jeffrey Jacobson

Infectious diseases, HIV, immunology (secondary appointment).

Stephen Jennings

Optimal protection from HSV-1 infection provided by interactions between innate and acquired immune responses.

Suresh Joshi

Surgical site infections, bacterial pathogenesis and novel antibacterial agents, biodefense (secondary appointment).

Fred Krebs

Microbicide development, HIV-1 transmission, HIV-1 immunopathogenesis and neurogenesis.

Michelle Kutzler

Translational research in vaccinology, immunology and infectious disease (secondary appointment).

Julio Martín-García

HIV-1 envelope-mediated fusion and entry, HIV neurotropism and neuropathogenesis.

Olimpia Meucci

NeuroAIDS (secondary appointment).

Sonia Navas-Martín

Molecular pathogenesis and evolution of RNA viruses. Animal models for viral infectious diseases.

Michael Nonnemacher

HIV-1, drugs of abuse, bone marrow, monocytes, transcription.

Shendra Passic

Microbicide development, HIV-1 transmission, HIV-1 immunopathogenesis and neuropathogenesis.

Vanessa Pirrone

Impact of age and HIV/HCV coinfection on HIV-1 replication, pathogenesis, and immune activation profiles.

Edward Schulman

Allergies, asthma, interstitial lung diseases (secondary appointment).

Laura Steel

Development of RNAi-based therapies for hepatitis B virus (HBV) and HIV-1.

Sandra Urdaneta-Hartmann

Microbicide development, mother-to-child-transmission of HIV-1 through breast milk, sexually transmitted infections, women's health.

Brian Wigdahl

Immunopathogenesis and neuropathogenesis of HIV-1 and HTLV-I infection, transcriptional regulation of retroviral expression, viral sequence diversity and correlations to disease, development of microbicidal agents.

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Doylestown Campus
Drexel Institute for Biotechnology and Virology Research

Faculty

Research

Timothy Block

Molecular mechanisms of viral persistence and development of therapeutic strategies for hepatitis B virus (HBV) and herpes simplex virus (HSV).

Jinhong Chang

The study of microRNA on virus replication and development of small molecule antivirals and innate immune modulators

Maryann Comunale

Use of glycoproteomics for the identification of early detection markers for liver cancer.

Haitao Guo

Molecular pathway of HBV cccDNA formation and cccDNA regulation by viral and cellular factors; Development of in vitro assay systems for discovery of novel antiviral drugs.

Ju-Tao Guo

Molecular mechanisms of HBV replication and regulation, innate immunity against virus infection, and discovery of antiviral and host innate immune modulatory agents.

Pooja Jain

Dendritic cells in autoimmune and neuroinflammatory disease.

Zafar K. Khan

Animal modeling of microbial infections and neuroinflammation.

Anand Mehta

Development of new hepatitis B (HBV) therapeutics; identification of early markers of liver cancer.

Brad Nefsky

Identify novel biomarkers for hepatocellular carcinoma and determine the cause and consequence of hyperfucosylation of serum glycoproteins in hepatocellular carcinoma.

Pamela Norton

Development of novel antiviral drugs for use against hepatitis B virus (HBV) infection; host cell defenses against HBV infection.

Ying-Hsiu Su

Understanding interactions between herpes simplex virus type 1 (HSV-1) and neurons during viral latency and reactivation; using nucleic acids in urine as diagnostic markers of cancer.

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Allegheny General Hospital
Allegheny-Singer Research Institute Center for Genomic Sciences
Pittsburgh, PA

Faculty

Research

Farrel Joel Buchinsky

Determining genetic susceptibility of recurrent respiratory papillomatosis.

Garth D. Ehrlich

Molecular pathogenesis of chronic infectious diseases.

Fen Z. Hu

Bacterial biofilm pathogenesis.

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Fox Chase Cancer Center

Faculty

Research

Glenn Rall

Pathogenesis of neurotropic viral infections (secondary appointment).

 

 

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