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Faculty

Queen Lane Campus

Carol Artlett

Role of 3-deoxyglucosone in mediating inflammation in diabetes and autoimmunity and the role of the inflammasome in systemic sclerosis

Lawrence W. Bergman

Malarial invasion mechanisms and cellular gene expression patterns during infection
Elizabeth Blankenhorn Genetic foundations for inherited susceptibility to autoimmune diseases, including diabetes and multiple sclerosis
Alina Boesteanu Migration of dendritic cells to the lung after influenza virus infection, and the role of costimulatory molecules in the primary, secondary and memory immune responses to influenza virus
James Burns Development of protective immunity against blood-stage malaria induced by immunization with defined subunit vaccines
Thomas Edlind Molecular mechanisms of antifungal action, resistance, and toxicity
Santosh Katiyar Molecular mechanisms of antifungal resistance
Peter Katsikis Roles of cytokines, T cells, and apoptosis in autoimmunity and anti-viral immune responses
Sandhya Kortagere

Development and application of computational tools in drug discovery

Kirsten Larson Course director of medical immunology and medical genetics, and development and implementation of both team-taught courses in our medical school curricula
Yvonne Mueller Function of virus-specific cytotoxic CD8+ T cells
Richard Rest Molecular and cellular mechanisms of the pathogenesis of Neisseria gonorrhoeae, Neisseria meningitidis, and Bacillus anthracis
Donna Russo Director of the medical school curriculum, Interdisciplinary Foundations of Medicine, as well as department course director for Medical Microbiology
Daniel Simon Bacillus anthracis and regulation of its virulence genes
Akhil Vaidya Understanding basic molecular functioning of malaria parasites with a view to develop new antimalarial drugs

Center City Campus

Richard Huneke

Utilization and overview of animal models in biological research
Stephen Jennings Optimal protection from HSV-1 infection provided by interactions between innate and acquired immune responses
Fred Krebs HIV-1 immunopathogensis and neuropathogenesis, development of microbicidal agents

Julio Martín-García

HIV-1 envelope-mediated fusion and entry, HIV neurotropism and neuropathogenesis

Sonia Navas-Martín Molecular pathogenesis and evolution of RNA viruses. Animal models for viral infectious diseases.
Michael Nonnemacher Impact of genetic variation and drugs of abuse on HIV-1 and SIV replication and pathogenesis

Laura Steel

Development of RNAi-based therapies for hepatitis B virus (HBV)
Brian Wigdahl

Immunopathogenesis and neuropathogenesis of HIV-1 and HTLV-I infection, transcriptional regulation of retroviral expression, viral sequence diversity and correlations to disease, development of microbicidal agents

Doylestown Campus
Drexel Institute for Biotechnology and Virology Research

Tim Block

Molecular mechanisms of viral persistence and development of therapeutic strategies for hepatitis B virus (HBV) and herpes simplex virus (HSV)
Haitao Guo Molecular pathway of HBV cccDNA formation and cccDNA regulation by viral and cellular factors; Development of in vitro assay systems for discovery of novel antiviral drugs.
Pooja Jain Dendritic cells in autoimmune and neuroinflammatory disease
Zafar K. Khan Animal modeling of microbial infections and neuroinflammation

Xuanyong Lu

Cellular susceptibility to hepatitis B (HBV) infection; developing strategies to control cancer cell growth through silencing of overexpressed apoptosis inhibitors
Anand Mehta Development of new hepatitis B (HBV) therapeutics; identification of early markers of liver cancer

Pamela Norton

Development of novel antiviral drugs for use against hepatitis B virus (HBV) infection; host cell defenses against HBV infection

Ying-Hsiu Su

Understanding interactions between herpes simplex virus type 1 (HSV-1) and neurons during viral latency and reactivation; using nucleic acids in urine as diagnostic markers of cancer

Allegheny General Hospital
Allegheny-Singer Research Institute
Center for Genomic Sciences
Pittsburgh, PA

Farrel Joel Buchinsky

Determining genetic susceptibility of recurrent respiratory papillomatosis
Garth D. Ehrlich

Molecular pathogenesis of chronic infectious diseases

Fen Z. Hu Bacterial Biofilm Pathogenesis
Sandeep Kathju Gene regulation during scarless wound healing

James Christopher Post

Role of biofilms in chronic human infections using otitis media as a model. Genetics of human performance, scarless wound healing.

Secondary Faculty

Michael Bouchard Molecular mechanisms through which HBx influences cellular signaling
cascades and the consequences of this for HBV replication and the
development of liver cancer
Jeffery Jacobson

Immune cell-based vaccines as therapies for HIV infection and novel
inhibitors of cell entry against HIV

Michelle Kutzler Develop next generation optimized DNA vaccine based strategies that target
antigen-specific cellular and humoral immune responses to mucosal sites
Edward Schulman