Randomized Controlled Trials:

What do they have to do with you?

2/27/01

MCP Hahnemann Pediatric Neurosurgery HOME

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Table of Contents

Randomized Controlled Trials What do they have to do with you?

PPT Slide

The patients in the RCT must be like your patient.

Medulloblastoma

EC / IC Bypass

Nimodipine for Head Injury

Other treatment measures must be similar to your practice.

Antifibrinolytics

The experimental treatment must be relevant to your practice.

Barbiturate Coma

The outcomes reported for the standard treatment must make sense.

Antibiotic prophylaxis

The outcomes measured must be important clinically.

Hyperbaric Oxygen

“Surrogate” End-points - examples

Surrogate End-points

Author: Joseph Piatt

Email: joseph.piatt@drexel.edu

Home Page: http://www.mcphu.edu/medschool/depts/neurosurgery/ped/mcphupns.htm

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