Randomized Controlled Trials What do they have to do with you?
PPT Slide
The patients in the RCT must be like your patient.
Medulloblastoma
EC / IC Bypass
Nimodipine for Head Injury
Other treatment measures must be similar to your practice.
Antifibrinolytics
The experimental treatment must be relevant to your practice.
Barbiturate Coma
The outcomes reported for the standard treatment must make sense.
Antibiotic prophylaxis
The outcomes measured must be important clinically.
Hyperbaric Oxygen
“Surrogate” End-points - examples
Surrogate End-points